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Go to the first pageLASER TREATMENT FOR SKIN DISEASES- 2 - MATERIALS AND METHODS From 1985 to, 1996 the total number of the patients treated by us using different laser systems was 1544 (2622 skin lesions). High power lasers - Nd:YAG and C02 lasers were used by us only for surgical treatment. Low power lasers: Helium-Neon (He-Ne) laser. Copper vapour pumped dye laser with Rhodamines and Gold vapour laser which were applied by us to: photodynamic therapy of malignant tumors, and biostimulation for healing wounds and regeneration of tissues. As regards the Copper vapour laser, we applied it to the treatment of pigmented skin lesions and port-wine hemangiomas. Table 2 lists the types of the laser used by us in dermatological surgery and therapy. The number of skin lesions treated with each type the laser is showed in Table_3. Table 2. Lasers used by us in dermatology
Table 3. Number of patients and skin lesions treated with different laser types type
There were 1143 malignant tumours and 1479 benign lesions among all the skin lesions treated by us with different laser types. Photodynamic therapy (PDT), i.e. laser excitation of photosensitizer localized in tumour was applied by us only to: malignant melanoma's treatment (38 lesions), metastatical skin lesion's treatment (22 lesions) advanced skin carcinoma's T3-T4 (34 foci) and residual or recurrent skin carcinoma's (101 lesions) treatment. Speaking about surgical laser treatment with Nd: YAG or CO2 lasers, we provided this treatment for the patients with T1-2 basal cell carcinoma (693 foci) for the patients with T1-2 squamous cell carcinoma and for the patients with benign tumours (1406), too. Copper vapour laser was used only in vascular lesions treatment (33 lesions). Helium-Neon and Gold vapour lasers alone (without photosensitizers) were applied to biostimulation for healing wounds and regenerations of tissues (40 lesions). Table 4 presents our laser treatment experience in dermatology. Table 4. Laser treatment Experience in Dermatology
All surgical laser treatment procedures, except two" woe provided with local anesthesia. 2% lignocaine solution usually was used during the surgical procedures. Low power laser therapy (without photosensitizers) can provide analgesia for the pain itself. PDT for about 60% of the total number of the treated patients was painful. For the other it was painless. During POT usually general analgesia with i/m injection of Baralgine solution was used. The total number of 1544 patients were treated. There were 604 male and 940 female among them. Speaking about the ^e of the patients it should be said that there were 11 patients under 3, 23 were at the age from 3 to 7. 104 were aged from 8 to 15, 376 were from 16 to 30" 651 were aged from 31 to 60, 335 were between 61 and 79 and 44 patients were over 80. There were 674 patients with malignant tumours and 870 ones with benign skin lesions. All these patients suspected with malignant diseases had to pass morphological examionations. Those who turned out to have proved malignances entered the study. Most of them were seen four or six weeks later the laser treatment and were taken care of by us for 13-5 years. The minimum frequency of follow up was recommended twice a year. Most patients with vasculas lesions were seen from three to six months later the laser treatment The patients with nevi were seen from two to six months later the laser treatment. |